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Definition |
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Gastroesophageal reflux disease (GERD) is a digestive disorder that is
caused by gastric acid flowing from the stomach into the esophagus.
Gastroesophageal refers to the stomach and esophagus, and reflux means to
flow back or return. Gastroesophageal reflux (GER) is the return of acidic
stomach juices, or food and fluids, back up into the esophagus.

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Causes |
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GERD is
believed to be the result of condition called hiatal hernia, which affects
the lower esophageal sphincter (LES). The typical cause of heartburn is when
acid from the stomach backs up into the esophagus. The LES, a muscle located
at the bottom of the esophagus, opens to let food in and closes to keep it
in the stomach. When this muscle relaxes too often or for too long, acid
refluxes back into the esophagus, causing heartburn.
Other
lifestyle contributors to GERD may include the following:
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being overweight
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overeating
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consuming certain foods,
such as citrus, peppermint, chocolate, fatty, and spicy foods
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caffeine
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alcohol
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smoking
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use of nonsteroidal
anti-inflammatory (NSAIDs) drugs such as aspirin and ibuprofen
Other
medical causes of heartburn may include the following:
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gastritis - an
inflammation of the stomach lining.
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ulcer disease
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Symptoms |
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The
following is the most common symptom of GERD. However, each individual may
experience symptoms differently.
Heartburn,
also called acid indigestion, is the most common symptom of GERD.
Heartburn is described as a burning chest pain that begins behind the
breastbone and moves upward to the neck and throat. It can last as long as
two hours and is often worse after eating. Lying down or bending over can
also result in heartburn.
Heartburn
pain is less likely to be associated with physical activity.
The
symptoms of GERD may resemble other medical conditions or problems. Always
consult your physician for a diagnosis.
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Diagnosis |
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In addition to a complete medical history and physical
examination, diagnostic procedures for GERD may include the following:
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upper GI
(gastrointestinal) series (Also called barium swallow.)
- a diagnostic test that examines the organs of the upper part of the
digestive system: the esophagus, stomach, and duodenum (the first section
of the small intestine). A fluid called barium (a metallic, chemical,
chalky, liquid used to coat the inside of organs so that they will show up
on an x-ray) is swallowed. X-rays are then taken to evaluate the digestive
organs.
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esophagogastroduodenoscopy (Also called EGD or upper endoscopy.)
An EGD
(upper endoscopy) is a procedure that allows the physician to examine the
inside of the esophagus, stomach, and duodenum. A thin, flexible, lighted
tube, called an endoscope, is guided into the mouth and throat, then into
the esophagus, stomach, and duodenum. The endoscope allows the physician to
view the inside of this area of the body, as well as to insert instruments
through a scope for the removal of a sample of tissue for biopsy (if
necessary).



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Bernstein test
- a test that helps to confirm that the symptoms are a result of acid in
the esophagus. The test is performed by dripping a mild acid through a tube
placed in the esophagus.
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esophageal manometry
- this test helps determine the strength of the muscles in the esophagus.
It is useful in evaluating gastroesophageal reflux and swallowing
abnormalities. A small tube is guided into the nostril, then passed into
the throat, and finally into the esophagus. The pressure the esophageal
muscles produce at rest is then measured.
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pH monitoring
- measures the acidity inside of the esophagus. It is helpful in evaluating
gastroesophageal reflux disease (GERD). A thin, plastic tube is placed into
a nostril, guided down the throat, and then into the esophagus. The tube
stops just above the lower esophageal sphincter, which is at the connection
between the esophagus and the stomach. At the end of the tube inside the
esophagus is a sensor that measures pH, or acidity. The other end of the
tube outside the body is connected to a monitor that records the pH levels
for a 12 to 24 hour period. Normal activity is encouraged during the study,
and a diary is kept of symptoms experienced, or activity that might be
suspicious for reflux, such as gagging or coughing. The pH readings are
evaluated and compared to the patient's activity for that time period.
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Treatment |
Specific
treatment for GERD will be determined by your physician based on:
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your age, overall health,
and medical history
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extent of the condition
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your tolerance for
specific medications, procedures, or therapies
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expectations for the
course of the condition
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your opinion or
preference
In many
cases, GERD can be relieved through diet and lifestyle changes, as directed
by your physician. Some ways to manage heartburn include the following:
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Monitor the medications
you are taking - some may irritate the lining of the stomach or esophagus.
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Watch food intake and
limit fried and fatty foods, peppermint, chocolate, alcohol, coffee, citrus
fruit and juices, and tomato products.
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Watch consumption of
alcohol.
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Do not lay down or go to
bed right after a meal. Instead, wait a couple of hours.
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Lose weight, if
necessary.
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Elevate the head of the
bed 6 inches.
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Take an antacid, as
directed by your physician.
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Ask your physician about
use of over-the-counter medicines called "H2-blockers." Formerly available
only by prescription, these drugs can be taken before eating to prevent
heartburn from occurring.
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Occasionally, a surgical
procedure called fundoplication may be performed to increase pressure on
the esophagus.
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More Resources |
National Institutes of Health
http://digestive.niddk.nih.gov/ddiseases/pubs/gerd/ |
VCU Health System
http://www.vcuhealth.org/content.asp?pageid=P00390 |
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